Intramolecular functional group differentiation as a strategy for the synthesis of bridged bicyclic β-amino acids-Reference-Cited by-同舟云学术

Intramolecular functional group differentiation as a strategy for the synthesis of bridged bicyclic β-amino acids

Published:2016 Issue:27 Volume:6 Page:22737-22748
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Tymtsunik Andriy V.¹²³⁴⁵,Kokhan Serhii O.¹²³⁴⁵,Ivon Yevhen M.¹²³⁴⁵,Komarov Igor V.¹²³⁴⁵,Grygorenko Oleksandr O.¹²³

Affiliation:

1. National Taras Shevchenko University of Kyiv

2. Kyiv 01601

3. Ukraine

4. Enamine Ltd.

5. Kyiv 01103

Abstract

Differentiation of identical electrophilic functional groups (carboxylates) by a strategically placed internal nucleophile (an amino group) in cyclic precursors was used as a key general approach to functionalized azabicyclic scaffolds.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA01548D

Reference40 articles.

1. Quantifying the chemical beauty of drugs

2. Bicyclic Conformationally Restricted Diamines

3. Peptidomimetics, a synthetic tool of drug discovery

4. Conformationally Restricted Peptides as Tools in Opioid Receptor Studies

5. Conformationally rigid cyclic α-amino acids in the design of peptidomimetics, peptide models and biologically active compounds

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