Lewis acid catalyzed annulation of spirocyclic donor–acceptor cyclopropanes with exo-heterocyclic olefins: access to highly functionalized bis-spirocyclopentane oxindole frameworks

Author:

Singh Kuldeep12345,Pramanik Sourav12345,Hamlin Trevor A.6789ORCID,Mondal Biplab12345,Das Dinabandhu10115ORCID,Saha Jaideep12345ORCID

Affiliation:

1. Division of Molecular Synthesis and Drug Discovery

2. Centre of Biomedical Research

3. SGPGIMS Campus

4. Lucknow-226014

5. India

6. Department of Theoretical Chemistry and Amsterdam Center for Multiscale Modeling (ACMM)

7. Vrije Universiteit Amsterdam

8. 1081 HV Amsterdam

9. The Netherlands

10. School of Physical Sciences

11. Jawaharlal Nehru University

Abstract

Oxindole-activated spiro-DAC is used as synthon to prepare complex bis-spirocyclopentane oxindole frameworks via ring-enlargement.

Funder

Science and Engineering Research Board

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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