Selective modification of natural nucleophilic residues in peptides and proteins using arylpalladium complexes-Reference-Cited by-同舟云学术

Selective modification of natural nucleophilic residues in peptides and proteins using arylpalladium complexes

Published:2018 Issue:21 Volume:5 Page:3186-3193
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Cheng Wan-Min¹²³⁴⁵,Lu Xi¹²³⁴⁵^ORCID,Shi Jing¹²³⁴⁵,Liu Lei⁶⁷⁸⁹¹⁰^ORCID

Affiliation:

1. Hefei National Laboratory for Physical Sciences at the Microscale

2. CAS Key Laboratory of Urban Pollutant Conversion

3. Anhui Province Key Laboratory of Biomass Clean Energy

4. iChEM

5. University of Science and Technology of China

6. Tsinghua-Peking Center for Life Sciences

7. MOE Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology

8. Department of Chemistry

9. Tsinghua University

10. Beijing 100084

Abstract

The present review outlines the recent methodologies for selective arylation of natural nucleophilic residues within unprotected peptides and proteins promoted by arylpalladium complexes, which demonstrate the advantages and potential of organometallic palladium complexes in bioconjugation.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Anhui Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00765A

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