Design and synthesis of new fluconazole analogues-Reference-Cited by-同舟云学术

Design and synthesis of new fluconazole analogues

Published:2015 Issue:23 Volume:13 Page:6551-6561
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Pore Vandana S.¹²³⁴,Agalave Sandip G.¹²³⁴,Singh Pratiksha⁵⁶⁷⁸⁴,Shukla Praveen K.⁵⁶⁷⁸⁴,Kumar Vikash⁹¹⁰⁷⁸⁴,Siddiqi Mohammad I.⁹¹⁰⁷⁸⁴

Affiliation:

1. Organic Chemistry Division

2. CSIR-National Chemical Laboratory

3. Pune 411 008

4. India

5. Medical Mycology Lab.

6. Division of Fermentation Technology

7. CSIR-Central Drug Research Institute

8. Lucknow

9. Computational Bio & Bioinformatics Lab.

10. Division of Molecular & Structural Biology

Abstract

The synthesis of new fluconazole analogues containing two different 1,2,3-triazole units and an amide group is described. All the compounds showed very high antifungal activity and no toxicity.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/OB/C5OB00590F

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