Exercise-promoted adiponectin secretion activates autolysosomes to protect the liver of ApoE<sup>−/−</sup> mice from a high-fat diet-Reference-Cited by-同舟云学术

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Exercise-promoted adiponectin secretion activates autolysosomes to protect the liver of ApoE^−/− mice from a high-fat diet

Published:2024 Issue: Volume: Page:
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Wu Weijia¹^ORCID,Jian Ye¹,Yuan Shunling²,Li Xuan¹,Tang Yingzhe¹,Zeng Fanqi¹,Liu Wenjing¹,Zhao Zhe¹,Wang Yirong³,Wang Yiyang¹,Liu Wenfeng¹^ORCID

Affiliation:

1. Hunan Provincial Key Laboratory of Physical Fitness and Sports Rehabilitation, Hunan Normal University, Changsha 410012, China

2. Yangtze University, College of Arts and Sciences, Jingzhou 434020, China

3. Hunan Sports Vocational College, Changsha 410019, China

Abstract

Treadmill exercise promotes liver fat uptake, activates lipolysis and inhibits DNL, and activates autolysosomes through APN-AdipoR1 to accelerate lipolysis and protect hepatocytes from lipotoxicity.

Funder

Natural Science Foundation of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/FO/D4FO02984D

Reference75 articles.

1. Molecular mechanisms of metabolic associated fatty liver disease (MAFLD): functional analysis of lipid metabolism pathways

2. An adipocentric perspective on the development and progression of non-alcoholic fatty liver disease

3. The prevalence and incidence of NAFLD worldwide: a systematic review and meta-analysis

4. NAFLD and NASH: etiology, targets and emerging therapies

5. Improvement in histological endpoints of MAFLD following a 12-week aerobic exercise intervention

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