Point-of-care detection of sevoflurane anesthetics in exhaled breath using a miniature TOFMS for diagnosis of postoperative agitation symptoms in children

Author:

Liu Bing1,Tang Wenxi2,Li Hang3ORCID,Liu Ruidong1,Dong Fengshuo1,Guo Yingzhe1,Li Jianjun2,Hou Keyong1ORCID

Affiliation:

1. Environment Research Institute, Shandong University, 72 Binhai Road, Qingdao 266237, People's Republic of China

2. Department of Anesthesiology, Qilu Hospital (Qingdao), Cheeloo College of Medicine, Shandong University, Qingdao, 758 Hefei Road, Qingdao 266035, People's Republic of China

3. Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian 116023, People's Republic of China

Abstract

A miniature TOFMS with MEPEI has been developed for POC diagnosis of postoperative agitation symptoms, and can analyze sevoflurane by direct sampling. The risk is high when the sevoflurane in the exhaled breath is higher than 500 ppmv.

Funder

National Key Scientific Instrument and Equipment Development Projects of China

National Natural Science Foundation of China

Taishan Scholar Foundation of Shandong Province

Qingdao Key Health Discipline Development Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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