A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding-Reference-Cited by-同舟云学术

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

Published:2014 Issue:31 Volume:50 Page:4056-4058
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Mangrum John B.¹²³,Engelmann Brigitte J.¹²³,Peterson Erica J.¹²³,Ryan John J.⁴²³,Berners-Price Susan J.⁵⁶⁷,Farrell Nicholas P.¹²³⁵⁶

Affiliation:

1. Department of Chemistry

2. Virginia Commonwealth University

3. Richmond, USA

4. Department of Biology

5. Institute for Glycomics

6. Griffith University

7. Gold Coast, Australia

Abstract

Metalloglycomics – the effects of defined coordination compounds on oligosaccharides and their structure and function opens new areas for bioinorganic chemistry and expands its systematic study to the third major class of biomolecules after DNA/RNA and proteins.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C3CC49695C

Reference25 articles.

1. The Structure of Glycosaminoglycans and their Interactions with Proteins

2. The sweet and sour of cancer: glycans as novel therapeutic targets

3. Mammalian heparanase: involvement in cancer metastasis, angiogenesis and normal development

4. Therapeutic value of glycosaminoglycans in cancer

5. A Synthetic Antithrombin III Binding Pentasaccharide Is Now a Drug! What Comes Next?

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