Thermodynamics of amyloid fibril formation from chemical depolymerization
Author:
Affiliation:
1. Institut for Physical Biology
2. Heinrich-Heine-Universitaet Duesseldorf
3. Duesseldorf
4. Germany
5. Technical University of Denmark
Abstract
Amyloid fibrils are homo-molecular protein polymers. Here we present an experimental and conceptual framework to study their thermodynamic stability that is consistent with the nature of amyloid fibrils as nucleated polymers.
Funder
Novo Nordisk Fonden
Deutsche Forschungsgemeinschaft
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2019/CP/C9CP04524D
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