Polymer-supported synthesis of N-substituted anthranilates as the building blocks for preparation of N-arylated 3-hydroxyquinolin-4(1H)-ones
Author:
Affiliation:
1. Department of Organic Chemistry
2. Faculty of Science
3. Palacký University
4. 77146 Olomouc
5. Czech Republic
6. Institute of Molecular and Translational Medicine
7. Faculty of Medicine and Dentistry
8. 77900 Olomouc
Abstract
Fast and simple access to N-arylated 3-hydroxyquinolin-4(1H)-ones starting from easily available 1-methyl-2-iodoterephthalate and variously substituted anilines is presented.
Funder
Grantová Agentura České Republiky
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA01308D
Reference36 articles.
1. Fluorinated derivatives of 2-phenyl-3-hydroxy-4(1H)-quinolinone as tubulin polymerization inhibitors
2. Identification of Eukaryotic Translation Elongation Factor 1-α 1 Gamendazole-Binding Site for Binding of 3-Hydroxy-4(1H)-quinolinones as Novel Ligands with Anticancer Activity
3. 3-Hydroxy-2-phenyl-4(1H)-quinolinones as Promising Biologically Active Compounds
4. Synthesis of 2-Aryl-3-hydroxyquinolin-4(1H)-ones
5. Efficient Solid-Phase Synthesis of 2-Substituted-3-Hydroxy-4(1H)-Quinolinone-7-Carboxamides with Two Diversity Positions
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