Simultaneous NMR characterisation of multiple minima in the free energy landscape of an RNA UUCG tetraloop
Author:
Affiliation:
1. Department of Chemistry
2. University of Cambridge
3. Cambridge CB2 1EW
4. UK
5. Departments of Molecular Genetics
6. Biochemistry
7. and Chemistry
8. University of Toronto
9. Toronto
Abstract
RNA molecules in solution tend to undergo structural fluctuations of relatively large amplitude and to populate a range of different conformations some of which are difficult to characterize because of their low populations.
Publisher
Royal Society of Chemistry (RSC)
Subject
Physical and Theoretical Chemistry,General Physics and Astronomy
Link
http://pubs.rsc.org/en/content/articlepdf/2017/CP/C6CP08313G
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1. Resolving the Motional Modes That Code for RNA Adaptation
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