In vivo self-assembled shape-memory polyurethane for minimally invasive delivery and therapy

Author:

Li Shifen1,Zhang Hua2,Xie Jieqi1,Wang Zhaoyi1,Wang Kai1,Zhai Zihe1,Ding Jie1,Wang Shuqin1,Shen Liyin1,Wen Jun3,Tang Yi-Da3,Wang Huanan2,Zhu Yang1,Gao Changyou14ORCID

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization, International Research Center for X Polymers, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China

2. College of Animal Science, Zhejiang University, Hangzhou 310058, China

3. Department of Cardiology and Institute of Vascular Medicine, Peking University Third Hospital, Key Laboratory of Molecular Cardiovascular Science, Ministry of Education, Beijing, 100191, China

4. Center for Healthcare Materials, Shaoxing Institute, Zhejiang University, Shaoxing 312099, China

Abstract

Advanced elastomers are highly demanded for the fabrication of medical devices for minimally invasive surgery (MIS). A diselenide-containing, shape-memory and self-healing polyurethane for MIS is illustrated in myocardial infarction therapy.

Funder

Natural Science Foundation of Zhejiang Province

Primary Research and Development Plan of Zhejiang Province

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrical and Electronic Engineering,Process Chemistry and Technology,Mechanics of Materials,General Materials Science

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