Spontaneous resolution of <i>RS</i>-fluoxetine through tetrafluoroborate conglomerate salt and racemic kryptoracemate formation <i>via</i> the sulfate ion-Reference-Cited by-同舟云学术

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Spontaneous resolution of RS-fluoxetine through tetrafluoroborate conglomerate salt and racemic kryptoracemate formation via the sulfate ion

Published:2024 Issue: Volume: Page:
ISSN:1466-8033
Container-title:CrystEngComm
language:en
Short-container-title:CrystEngComm

Author:

Carvalho Paulo S.¹^ORCID,Diniz Luan F.²,Fernandes Christian²^ORCID

Affiliation:

1. Institute of Physics, Federal University of Mato Grosso do Sul, 79070-900, Campo Grande, MS, Brazil

2. Faculty of Pharmacy, Federal University of Minas Gerais, 31270-901, Belo Horizonte, Brazil

Abstract

RS-Fluoxetine spontaneously resolves into a conglomerate via tetrafluoroborate salt formation. Sulfate anion produces a kryptoracemate with homochiral chains but lacks enantiomeric discrimination.

Funder

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/CE/D4CE00643G

Reference52 articles.

1. Chiral Toxicology: It's the Same Thing…Only Different

2. E. L. W.Francotte , in Chirality in drug research , ed. E. Francotte and W. Lindner , Wiley-VCH. , Weinheim, Germany , 2006

3. Chiral Drugs. An Overview

4. Chirality and its implications for the pharmaceutical industry

5. J. J.Collet Andr and S. H.Wilen , Enantiomers, racemates, and resolutions , Wiley , New York , 1981

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