Synthesis of tumor-associated MUC1-glycopeptides and their multivalent presentation by functionalized gold colloids

Author:

Tavernaro Isabella1234,Hartmann Sebastian5674,Sommer Laura8234,Hausmann Heike5234,Rohner Christian1234,Ruehl Martin8234,Hoffmann-Roeder Anja59104,Schlecht Sabine1234

Affiliation:

1. Institute of Inorganic and Analytical Chemistry

2. Justus-Liebig-University Giessen

3. 35392 Giessen

4. Germany

5. Institute of Organic Chemistry

6. Johannes Gutenberg-University Mainz

7. 55128 Mainz

8. Institute of Food Chemistry and Food Biotechnology

9. Ludwig-Maximilian-University Munich

10. 81377 Munich

Abstract

The authors present the synthesis of novel MUC1-glycopeptide antigens and their multivalent presentation by gold colloids. Their biological activity was tested in a dot-blot immunoassay experiment.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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