Potential antitumoral 3,4-dihydropyrimidin-2-(1H)-ones: synthesis, in vitro biological evaluation and QSAR studies
Author:
Affiliation:
1. CICS-UBI – Health Sciences Research Centre
2. University of Beira Interior
3. 6201-001 Covilhã
4. Portugal
5. CNC – Center for Neuroscience and Cell Biology
6. University of Coimbra
7. 3004-517 Coimbra
8. Pharmacology Department
Abstract
The search for novel anticancer agents with higher selectivity and lower toxicity remains a medical need.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA14596E
Reference55 articles.
1. Strategies for Innovation in Multicomponent Reaction Design
2. Recent Developments in Isocyanide Based Multicomponent Reactions in Applied Chemistry
3. “Multi-component Reactions : Emerging Chemistry in Drug Discovery” ‘From Xylocain to Crixivan’
4. Recent advances in multicomponent reactions for diversity-oriented synthesis
5. Biologically active dihydropyrimidones of the Biginelli-type — a literature survey
Cited by 24 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. ZnAl2O4/SiO2 nanocatalyst: a new efficient catalyst for Biginelli reaction with a specific product under safe, green, and solvent-free conditions;Journal of the Iranian Chemical Society;2024-04-29
2. Bioactive Bismuth Compounds: Is Their Toxicity a Barrier to Therapeutic Use?;International Journal of Molecular Sciences;2024-01-27
3. Revisiting Biginelli-like reactions: solvent effects, mechanisms, biological applications and correction of several literature reports;Organic & Biomolecular Chemistry;2024
4. Tetrazolopyrimidine-tethered phenothiazine molecular hybrids: synthesis, biological and molecular docking studies;New Journal of Chemistry;2024
5. Theoretical study of the effect of the solvent on the electronic properties of pyrimidopyrimidine derivatives;Computational and Theoretical Chemistry;2023-09
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3