Detection of urinary microRNA biomarkers using diazo sulfonamide-modified screen printed carbon electrodes-Reference-Cited by-同舟云学术

Detection of urinary microRNA biomarkers using diazo sulfonamide-modified screen printed carbon electrodes

Published:2021 Issue:31 Volume:11 Page:18832-18839
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Smith Daniel A.¹²³⁴⁵^ORCID,Simpson Kate¹²³⁴⁵,Lo Cicero Matteo⁶⁷⁵⁸⁹,Newbury Lucy J.¹²³⁴⁵,Nicholas Philip¹⁰¹¹⁹,Fraser Donald J.¹²³⁴⁵,Caiger Nigel¹⁰¹¹⁹,Redman James E.¹²¹³⁹⁶⁷^ORCID,Bowen Timothy¹²³⁴⁵^ORCID

Affiliation:

1. Wales Kidney Research Unit

2. Division of Infection & Immunity

3. School of Medicine

4. College of Biomedical and Life Sciences

5. Cardiff University

6. School of Chemistry

7. College of Physical Sciences and Engineering

8. Cardiff CF10 3AT

9. UK

10. Sun Chemical Ltd

11. Bath BA3 4RT

12. Cardiff Institute of Tissue Engineering and Repair

13. Cardiff CF10 3BG

Abstract

In this study we have developed an electrochemical microRNA biosensor sensitive to 17 fM and capable of detecting an established downregulation of urinary miR-192 in diabetic kidney disease patients.

Funder

Kidney Research UK

Wellcome Trust

Cardiff University

Biotechnology and Biological Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA09874D

Reference39 articles.