Redox responsive Pluronic micelle mediated delivery of functional siRNA: a modular nano-assembly for targeted delivery

Author:

Kadekar Sandeep12345,Nawale Ganesh N.12345ORCID,Rangasami Vignesh K.12345ORCID,Le Joncour Vadim678910ORCID,Laakkonen Pirjo678910,Hilborn Jöns1134512,Varghese Oommen P.12345ORCID,Oommen Oommen P.1314151610ORCID

Affiliation:

1. Translational Chemical Biology Laboratory

2. Polymer Chemistry Division

3. Department of Chemistry – Ångström Laboratory

4. Uppsala University

5. Uppsala

6. Translational Cancer Medicine Research Program

7. Faculty of Medicine

8. University of Helsinki

9. Helsinki

10. Finland

11. Polymer Chemistry

12. Sweden

13. Bioengineering and Nanomedicine Group

14. Faculty of Medicine and Health Technologies

15. Tampere University

16. Tampere

Abstract

There is an unmet need to develop strategies that allow site-specific delivery of short interfering RNA (siRNA) without any associated toxicity. Here we report a modular delivery system that can be custom modified with targeting peptide and siRNAs.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Cited by 7 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3