Enzymatic macrocyclization of ribosomally synthesized and posttranslational modified peptides via C–S and C–C bond formation-Reference-Cited by-同舟云学术

Enzymatic macrocyclization of ribosomally synthesized and posttranslational modified peptides via C–S and C–C bond formation

Published:2021 Issue:5 Volume:38 Page:981-992
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Lu Jingxia¹²³⁴⁵,Li Yuqing¹²³⁴⁵,Bai Zengbing¹²³⁴⁵,Lv Hongmei¹²³⁴⁵,Wang Huan¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Coordination Chemistry

2. Chemistry and Biomedicine Innovation Center of Nanjing University

3. Jiangsu Key Laboratory of Advanced Organic Materials

4. School of Chemistry and Chemical Engineering

5. Nanjing University

Abstract

This review article summarizes recent progress in the macrocyclization of ribosomally synthesized and posttranslational modified peptides by C–S and/or C–C bond formation with a focus on the current understanding of the enzymatic mechanisms.

Funder

National Natural Science Foundation of China

Fundamental Research Funds for the Central Universities

Natural Science Foundation of Jiangsu Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NP/D0NP00044B

Reference88 articles.

1. New developments in RiPP discovery, enzymology and engineering

2. Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature

3. The anti-staphylococcal lipolanthines are ribosomally synthesized lipopeptides

4. Acyltransferase that catalyses the condensation of polyketide and peptide moieties of goadvionin hybrid lipopeptides

5. Cyclic peptide therapeutics: past, present and future

Cited by 15 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Mechanistic Insights into the Selective C–S Bond Formation by P450 TleB;ACS Catalysis;2024-07-01

2. Daropeptide natural products;Exploration of Drug Science;2024-04-19

3. Promiscuity of Omphalotin A Biosynthetic Enzymes Allows de novo Production of Non‐Natural Multiply Backbone N‐Methylated Peptide Macrocycles in Yeast;ChemBioChem;2024-01-04

4. P450-Modified Ribosomally Synthesized Peptides with Aromatic Cross-Links;Journal of the American Chemical Society;2023-12-09

5. TRYPTOPHAN-specific peptide modification through metal-free photoinduced N-H alkylation employing N-aryl glycines;Chinese Chemical Letters;2023-10