Using membrane–water partition coefficients in a critical membrane burden approach to aid the identification of neutral and ionizable chemicals that induce acute toxicity below narcosis levels-Reference-Cited by-同舟云学术

Using membrane–water partition coefficients in a critical membrane burden approach to aid the identification of neutral and ionizable chemicals that induce acute toxicity below narcosis levels

Published:2023 Issue:3 Volume:25 Page:621-647
ISSN:2050-7887
Container-title:Environmental Science: Processes & Impacts
language:en
Short-container-title:Environ. Sci.: Processes Impacts

Author:

Droge Steven T. J.¹^ORCID,Hodges Geoff²^ORCID,Bonnell Mark³^ORCID,Gutsell Steve²^ORCID,Roberts Jayne²^ORCID,Teixeira Alexandre²^ORCID,Barrett Elin L.²^ORCID

Affiliation:

1. Department of Freshwater and Marine Ecology (FAME), Institute for Biodiversity and Ecosystem Dynamics (IBED), Universiteit van Amsterdam (UvA), Science Park 904, 1098XH Amsterdam, The Netherlands

2. Safety and Environmental Assurance Centre, Unilever, Colworth Science Park, Sharnbrook, Bedfordshire, UK

3. Environment and Climate Change Canada, Ecological Assessment Division, Science and Risk Assessment Directorate, Gatineau, Quebec, Canada

Abstract

The risk assessment of thousands of chemicals used in our society benefits from adequate grouping of chemicals based on the mode and mechanism of toxic action (MoA).

Funder

Unilever

Publisher

Royal Society of Chemistry (RSC)

Subject

Management, Monitoring, Policy and Law,Public Health, Environmental and Occupational Health,Environmental Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2023/EM/D2EM00391K

Reference106 articles.

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3. ECHA , ECHA Read across Framework (ECHA-17-R-01-EN) , European Chemicals Agency , ECHA , 2017

4. ECCC – Environmental and Climate Change Canada , Science Approach Document: Ecological Risk Classification of Organic Substances , ECCC – Environment and Climate Change Canada , Gatineau (QC) , 2016 , https://www.ec.gc.ca/ese-ees/default.asp?lang=En&n=a96e2e98-1

5. Environment and Climate Change Canada (ECCC) , Science Approach Document - Ecological Risk Classification of Organic Substances Version 2.0 (ERC2 , Government of Canada. ECCC, Gatineau , Quebec , 2022 , https://www.canada.ca/en/environment-climate-change/services/evaluating-existingsubstances/science-approach-document-ecological-risk-classification-organic-substances-erc2.html

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