Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery-Reference-Cited by-同舟云学术

Harmonized tuning of nucleic acid and lectin binding properties with multivalent cyclodextrins for macrophage-selective gene delivery

Published:2015 Issue:93 Volume:5 Page:76464-76471
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Méndez-Ardoy Alejandro¹²³⁴⁵,Díaz-Moscoso Alejandro⁶⁷⁸⁹^ORCID,Ortiz Mellet Carmen¹²³⁴⁵^ORCID,Di Giorgio Christophe¹⁰¹¹¹²¹³,Vierling Pierre¹⁰¹¹¹²¹³,Benito Juan M.⁶⁷⁸⁹,García Fernández José M.⁶⁷⁸⁹

Affiliation:

1. Departamento de Química Orgánica

2. Facultad de Química

3. Univ. Sevilla

4. C/Prof. García González 1

5. E-41012 Sevilla

6. Instituto de Investigaciones Químicas

7. CSIC – Univ. Sevilla

8. E-41092 Sevilla

9. Spain

10. Institut de Chimie de Nice

11. ICN – Université de Nice Sophia Antipolis – CNRS UMR 7272

12. F-06100 Nice

13. France

Abstract

Polycationic amphiphilic cyclodextrins (paCDs) have been shown to behave as efficient non-viral gene carriers paralleling the efficacy of commercial vectors towards a variety of cell lines.

Funder

Consejo Superior de Investigaciones Científicas

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16087A

Reference46 articles.

1. Nucleic acid therapeutics: basic concepts and recent developments

2. Non-Viral Nucleic Acid Delivery: Key Challenges and Future Directions

3. Nonviral Vectors for Gene Delivery