Aza-Michael promoted glycoconjugation of PETIM dendrimers and selectivity in mycobacterial growth inhibitions-Reference-Cited by-同舟云学术

Aza-Michael promoted glycoconjugation of PETIM dendrimers and selectivity in mycobacterial growth inhibitions

Published:2023 Issue:7 Volume:13 Page:4669-4677
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Sarkar Biswajit¹,Mahapa Avisek²³,Dey Kalyan¹,Manhas Rakshit³,Chatterji Dipankar²,Jayaraman Narayanaswamy¹^ORCID

Affiliation:

1. Department of Organic Chemistry, Indian Institute of Science, Bangalore 560 012, India

2. Molecular Biophysics Unit, Indian Institute of Science, Bangalore 560 012, India

3. Infectious Disease Department, CSIR-Indian Institute of Integrative Medicine, Jammu-180001, India

Abstract

Glycoconjugation of primary amine-terminated PETIM dendrimer generations 1 to 3 is conducted using a sugar vinyl sulfoxide as aza-Michael acceptor in aq. MeOH. The native and glycoconjugate dendrimers show selective mycobacterial growth inhibition.

Funder

Department of Biotechnology, Ministry of Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA08196B

Reference66 articles.

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3. Changes of glycoconjugate expression profiles during early development

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5. Chemical assembly of N-glycoproteins: a refined toolbox to address a ubiquitous posttranslational modification

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