The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy-Reference-Cited by-同舟云学术

The renoprotective effect of diosgenin on aristolochic acid I-induced renal injury in rats: impact on apoptosis, mitochondrial dynamics and autophagy

Published:2020 Issue:9 Volume:11 Page:7456-7467
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Jin Chengni¹²³⁴,Miao Xin¹²³⁴,Zhong Yujie¹²³⁴,Han Jiahui¹²³⁴,Liu Qi¹²³⁴,Zhu Jiachang¹²³⁴,Xia Xiaodong¹²³⁴,Peng Xiaoli¹²³⁴⁵^ORCID

Affiliation:

1. College of Food Science and Engineering

2. Northwest A&F University

3. Yangling

4. China

5. Beijing Advanced Innovation Center for Food Nutrition and Human Health

Abstract

Diosgenin relieved aristolochic acid I-induced renal injury in rats by suppressing apoptosis, maintaining mitochondrial dynamics equilibrium, and inhibiting autophagy.

Funder

National Natural Science Foundation of China

Beijing Advanced Innovation Center for Food Nutrition and Human Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2020/FO/D0FO00401D

Reference60 articles.

1. Chronic kidney disease: global dimension and perspectives

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3. Structure activity relationships of aristolochic acid analogues: Toxicity in cultured renal epithelial cells

4. DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

5. The Mutational Features of Aristolochic Acid–Induced Mouse and Human Liver Cancers

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