Not just a fluidifying effect: omega-3 phospholipids induce formation of non-lamellar structures in biomembranes

Author:

de Santis Augusta12345,Vitiello Giuseppe56478ORCID,Appavou Marie-Sousai9101112ORCID,Scoppola Ernesto131412ORCID,Fragneto Giovanna151617,Barnsley Lester C.9101112ORCID,Clifton Luke A.18192021,Ottaviani Maria Francesca2223244ORCID,Paduano Luigi12345,Russo Krauss Irene12345ORCID,D’Errico Gerardino12345ORCID

Affiliation:

1. Department of Chemical Sciences

2. University of Naples Federico II

3. Naples

4. Italy

5. CSGI (Consorzio per lo Sviluppo dei Sistemi a Grande Interfase)

6. Florence

7. Department of Chemical

8. Materials and Production Engineering, University of Naples Federico II

9. Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ)

10. Forschungszentrum Jülich GmbH

11. Garching

12. Germany

13. Max Planck Institut für Kolloid und Grenzflächenforschung

14. Potsdam

15. Institut Laue-Langevin (ILL)

16. Grenoble

17. France

18. ISIS Facility, Science and Technology Facilities Council

19. Rutherford Appleton Laboratory

20. Didcot OX11 0QX

21. UK

22. Department of Pure and Applied Sciences

23. University of Urbino

24. Urbino

Abstract

Beyond a threshold concentration, omega-3 phospholipid 22:6-22:6PC hampers the formation of a typical lamellar phase of lipid membranes forming small spherical aggregates.

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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