Enantioselective syntheses and application of 4-epi-galiellalactone and the corresponding activity-based probe: from strained bicycles to strained tricycles-Reference-Cited by-同舟云学术

Enantioselective syntheses and application of 4-epi-galiellalactone and the corresponding activity-based probe: from strained bicycles to strained tricycles

Published:2019 Issue:7 Volume:17 Page:1886-1892
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Lu Yandong¹²³⁴⁵,Zhao Shan⁶⁷⁵⁸⁹,Zhou Shijie⁶⁷⁵⁸⁹,Chen Si-Cong⁶⁷⁵⁸⁹,Luo Tuoping¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Bioorganic Chemistry and Molecular Engineering

2. Ministry of Education

3. Beijing National Laboratory for Molecular Science

4. College of Chemistry and Molecular Engineering

5. Peking University

6. Peking-Tsinghua Center for Life Sciences

7. Academy for Advanced Interdisciplinary Studies

8. Beijing 100871

9. China

Abstract

Efficient syntheses of 4-epi-galiellalactone and the corresponding activity-based probe enabled chemoproteomic studies to reveal the biological targets.

Funder

Peking University

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C8OB01915K

Reference46 articles.

1. Protein-Reactive Natural Products

2. Electrophilic natural products and their biological targets

3. Activity-Based Protein Profiling for Natural Product Target Discovery

4. Chemistry and biology of wortmannin

5. Enantioselective Total Synthesis of (+)-Wortmannin

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