Cytocompatible, soft and thick brush-modified scaffolds with prolonged antibacterial effect to mitigate wound infections

Author:

Dhingra Shaifali1,Gaur Vidit2,Saini Varsha3ORCID,Rana Kajal3ORCID,Bhattacharya Jayanta2,Loho Thomas4ORCID,Ray Sudip4,Bajaj Avinash3ORCID,Saha Sampa1ORCID

Affiliation:

1. Department of Materials Science and Engineering, Indian Institute of Technology Delhi, India

2. Centre for Biomedical Engineering, Indian Institute of Technology Delhi, India

3. Laboratory of Nanotechnology and Chemical Biology, Regional Centre For Biotechnology, India

4. Department of Chemical and Materials Engineering, The University of Auckland, New Zealand Institute for Minerals to Materials Research, India

Abstract

We report a new strategy for constructing highly antibacterial (zero bacterial growth) as well as cytocompatible (almost 100% cell viability), ultrasoft, mixed polymer brushes onto the surface of 3D printed scaffold made of biodegradable polymers.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Indian Council of Medical Research

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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