Towards optimised drug delivery: structure and composition of testosterone enanthate in sodium dodecyl sulfate monolayers

Author:

Saaka Yussif12345,Allen Daniel T.67385,Luangwitchajaroen Yuvared12345,Shao Yanan12345,Campbell Richard A.91011ORCID,Lorenz Christian D.67385ORCID,Lawrence M. Jayne12345ORCID

Affiliation:

1. Institute of Pharmaceutical Sciences

2. Faculty of Life Sciences and Medicine

3. King's College London

4. London SE1 9NH

5. UK

6. Department of Physics

7. Faculty of Natural and Mathematical Sciences

8. London WC2R 2LSJ

9. Institut Laue-Langevin

10. 38042 Grenoble

11. France

Abstract

Specular neutron reflectivity and molecular dynamic simulations have been used to study the interfacial structure and composition of monolayers of SDS containing a low-dose, poorly soluble drug, testosterone enanthate.

Funder

Engineering and Physical Sciences Research Council

Ghana Education Trust Fund

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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