Bifunctional squaramide catalyzed stereoselective Mannich reaction of α-azido ketones with isatin-derived ketimines

Author:

Karahan Seda1234ORCID,Tanyeli Cihangir1234ORCID

Affiliation:

1. Department of Chemistry

2. Middle East Technical University

3. Ankara

4. Turkey

Abstract

Bifunctional squaramide catalyzed asymmetric Mannich reaction of alpha-azido ketones and isatin derived ketiminines were established for the first time with high stereoselectivity. Adducts are valuable synthons for optically active heterocycles.

Funder

Türkiye Bilimsel ve Teknolojik Araştirma Kurumu

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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