An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles-Reference-Cited by-同舟云学术

An umpolung strategy for intermolecular [2 + 2 + 1] cycloaddition of aryl aldehydes and nitriles: a facile access to 2,4,5-trisubstituted oxazoles

Published:2022 Issue:27 Volume:13 Page:8080-8087
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Basavaiah Deevi¹^ORCID,Golime Gangadhararao¹,Banoth Shivalal¹,Todeti Saidulu¹

Affiliation:

1. School of Chemistry, University of Hyderabad, Hyderabad-500046, India

Abstract

An unprecedented intermolecular [2 + 2 + 1] cycloaddition strategy between two aryl aldehydes and a nitrile, wherein one of the aryl aldehydes serves as a carbanion (or equivalent) in the presence of TMSOTf for obtaining oxazole framework is presented.

Funder

Science and Engineering Research Board

University of Hyderabad

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC00046F

Reference64 articles.

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5. Generation and synthetic applications of 2-lithio-1,3-dithianes

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