Diblock- and triblock-copolymer based mixed micelles with high tumor penetration in vitro and in vivo
Author:
Affiliation:
1. Key Laboratory of Drug Targeting and Delivery
2. Ministry of Education
3. West China School of Pharmacy
4. Sichuan University
5. Chengdu
6. Department of Chemistry
7. The Scripps Research Institute
8. La Jolla
9. USA
Abstract
A series of self-assembled mixed micelles composed of TPGS and Pluronics were fabricated and their cellular uptake and exocytosis behaviors were studied in 2D cell and 3D tumor spheroid models.
Funder
Sichuan University
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2016/TB/C6TB00508J
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