Total synthesis of kealiiquinone: the regio-controlled strategy for accessing its 1-methyl-4-arylbenzimidazolone core

Author:

Ramadoss Velayudham12345ORCID,Alonso-Castro Angel J.16357ORCID,Campos-Xolalpa Nimsi89107ORCID,Ortiz-Alvarado Rafael1112137ORCID,Yahuaca-Juárez Berenice1112137ORCID,Solorio-Alvarado César R.12345ORCID

Affiliation:

1. Universidad de Guanajuato

2. Departamento de Química

3. División de Ciencias Naturales y Exactas

4. Campus Guanajuato

5. Guanajuato

6. Departamento de Farmacia

7. Mexico

8. Universidad Metropolitana

9. Unidad Xochimilco

10. México D.F.

11. Universidad Michoacana de San Nicolás de Hidalgo

12. Facultad de Químico Farmacobiología

13. Morelia

Abstract

A practical, concise and straightforward total synthesis of kealiiquinone 1, a naphtho[2,3-d]imidazole alkaloid obtained from the Micronesian marine sponge Leucetta sp. was accomplished.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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