Suppression of endoplasmic reticulum stress-associated pathways and hepatocyte apoptosis participates in the attenuation of betulinic acid on alcohol-provoked liver injury in mice-Reference-Cited by-同舟云学术

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Suppression of endoplasmic reticulum stress-associated pathways and hepatocyte apoptosis participates in the attenuation of betulinic acid on alcohol-provoked liver injury in mice

Published:2022 Issue:22 Volume:13 Page:11489-11502
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

He Enqi¹²,Ma Yurong¹³,Kong Li¹,Huang You¹,Huang Chunlin¹,Yang Wenjiang¹,Yi Jine¹,Zhu Lijuan¹^ORCID

Affiliation:

1. Hunan Engineering Research Center of Livestock and Poultry Health Care, College of Veterinary Medicine, Hunan Agricultural University, Changsha, 410128, China

2. College of Food Science and Technology, Hunan Agricultural University, Changsha, 410128, China

3. Changsha University of Science & Technology, Changsha 410114, China

Abstract

BA protects against alcohol-induced liver damage through the alleviation of oxidative stress and suppression of ERS-induced apoptosis.

Funder

Natural Science Foundation of Hunan Province

Development and Reform Commission of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01042A

Reference74 articles.

1. Global alcohol exposure between 1990 and 2017 and forecasts until 2030: a modelling study

2. miR‑148a‑3p regulates alcoholic liver fibrosis through targeting ERBB3

3. Pathogenesis of alcoholic liver disease

4. Endoplasmic reticulum stress signalling and the pathogenesis of non-alcoholic fatty liver disease

5. Astaxanthin from Haematococcus pluvialis ameliorates the chemotherapeutic drug (doxorubicin) induced liver injury through the Keap1/Nrf2/HO-1 pathway in mice

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1. Bioprospecting the liver protective activity of betulinic acid isolated from the stem bark of Ziziphus mucronata Willd. subsp. mucronata;Scientific African;2024-06

2. A novel approach combining network pharmacology and experimental validation to study the protective effect of ginsenoside Rb1 against cantharidin‐induced hepatotoxicity in mice;Basic & Clinical Pharmacology & Toxicology;2024-03-13

3. Depleted uranium induces thyroid damage through activation of ER stress via the thrombospondin 1-PERK pathway;Chemico-Biological Interactions;2023-09

4. Betulinic acid mitigates zearalenone-induced liver injury by ERS/MAPK/Nrf2 signaling pathways in mice;Food and Chemical Toxicology;2023-07

5. PI3K/AKT/mTOR, NF-κB and ERS pathway participated in the attenuation of H2O2-induced IPEC-J2 cell injury by koumine;Journal of Ethnopharmacology;2023-03

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