New insights into ethionamide metabolism: influence of oxidized methionine on its degradation path-Reference-Cited by-同舟云学术

New insights into ethionamide metabolism: influence of oxidized methionine on its degradation path

Published:2020 Issue:12 Volume:11 Page:1423-1428
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Vale Nuno¹²³⁴⁵^ORCID,Duarte Diana¹²³⁴⁶^ORCID,Correia Alexandra⁷⁸⁹¹⁰¹¹^ORCID,Alves Cláudia¹²¹³¹⁴¹⁵¹⁶^ORCID,Figueiredo Patrícia⁷⁸⁹¹⁰¹¹^ORCID,Santos Hélder A.⁷⁸⁹¹⁰¹¹^ORCID

Affiliation:

1. OncoPharma Research Group

2. Center for Health Technology and Services Research (CINTESIS)

3. 4200-450 Porto

4. Portugal

5. Faculty of Medicine

6. Laboratory of Pharmacology

7. Drug Research Program

8. Division of Pharmaceutical Chemistry and Technology

9. Faculty of Pharmacy

10. University of Helsinki

11. FI-00014 Helsinki

12. Department of Chemistry and Biochemistry

13. Faculty of Sciences

14. LAQV/REQUIMTE

15. University of Porto

16. Porto

Abstract

Ethionamide (ETH) is a commercial drug, used as a second-line resource to neutralize Mycobacterium tuberculosis infections.

Funder

Fundação para a Ciência e a Tecnologia

European Regional Development Fund

Sigrid Juséliuksen Säätiö

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/MD/D0MD00253D

Reference44 articles.

1. Metabolism and Pharmacokinetics of the Anti-Tuberculosis Drug Ethionamide in a Flavin-Containing Monooxygenase Null Mouse

2. Cancer statistics, 2015

3. Treatment and Prevention of Multidrug-Resistant Tuberculosis

4. Anticancer drug development: the grand challenges

5. Preparation and biological evaluation of ethionamide-mesoporous silicon nanoparticles against Mycobacterium tuberculosis

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