Isolation, identification and <i>in vivo</i> antihypertensive effect of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from <i>Spirulina</i> protein hydrolysate-Reference-Cited by-同舟云学术

Isolation, identification and in vivo antihypertensive effect of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from Spirulina protein hydrolysate

Published:2022 Issue:17 Volume:13 Page:9108-9118
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Suo Qishan¹²³^ORCID,Yue Yang¹²,Wang Jing¹²,Wu Ning¹²,Geng Lihua¹²,Zhang Quanbin¹²³

Affiliation:

1. CAS and Shandong Province Key Laboratory of Experimental Marine Biology, Center for Ocean Mega-Science, Institute of Oceanology, Chinese Academy of Sciences, Qingdao, China

2. Laboratory for Marine Biology and Biotechnology, Qingdao National Laboratory for Marine Science and Technology, Qingdao, China

3. University of Chinese Academy of Sciences, Beijing, China

Abstract

By combining virtual screening and experimental assay, two angiotensin I-converting enzyme inhibitory peptides, TVLYEH and LQAGGLF, were identified from the protease K hydrolysate of Spirulina protein, and TVLYEH showed significantly antihypertensive effect in vivo.

Funder

National Key Research and Development Program of China

Science and Technology Projects of Fujian Province

Natural Science Foundation of Shandong Province

Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO01207C

Reference43 articles.