Synthesis and structural investigation of 2-aminomethyl-3-(4-methoxy-phenyl)-propionic acid containing a peptide analogue of the amyloidogenic AS(6–7) sequence: inhibition of fibril formation

Author:

Paikar Arpita1234,Debnath Mintu1234,Podder Debasish1234,Sasmal Supriya1234,Haldar Debasish1234

Affiliation:

1. Department of Chemical Sciences

2. Indian Institute of Science Education and Research Kolkata

3. Mohanpur

4. India

Abstract

The incorporation of a β-amino acid, namely 2-aminomethyl-3-(4-methoxy-phenyl)-propionic acid, inhibits amyloid-like fibril formation.

Funder

Council of Scientific and Industrial Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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3. Foldamers:  A Manifesto

4. A Field Guide to Foldamers

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