Biomass-involved synthesis of N-substituted benzofuro[2,3-d]pyrimidine-4-amines and biological evaluation as novel EGFR tyrosine kinase inhibitors
Author:
Affiliation:
1. School of Pharmaceutical Sciences
2. Sun Yat-sen University
3. Guangzhou
4. People′s Republic of China
5. Zhongshan WanYuan New Drug R&D Co.
Abstract
Facile synthesis of N-substituted benzofuro[2,3-d]pyrimidine-4-amines from shikimic acid and biological evaluation as novel EGFR TKIs is described.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00793K
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