Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method-Reference-Cited by-同舟云学术

Neuropilin-1 peptide-like ligands with proline mimetics, tested using the improved chemiluminescence affinity detection method

Published:2019 Issue:2 Volume:10 Page:332-340
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Puszko Anna K.¹²³⁴^ORCID,Sosnowski Piotr⁵⁶⁷⁸⁴,Tymecka Dagmara¹²³⁴^ORCID,Raynaud Françoise⁹¹⁰¹¹¹²¹³,Hermine Olivier⁹¹⁰¹¹¹²¹³^ORCID,Lepelletier Yves⁹¹⁰¹¹¹²¹³^ORCID,Misicka Aleksandra¹²³⁴⁵^ORCID

Affiliation:

1. Faculty of Chemistry

2. University of Warsaw

3. 02-093 Warsaw

4. Poland

5. Department of Neuropeptides

6. Mossakowski Medical Research Centre

7. Polish Academy of Sciences

8. 02-106 Warsaw

9. Imagine Institute

10. Paris Descartes University–Sorbonne Paris Cité

11. 75015 Paris

12. France

13. Laboratory of Cellular and Molecular Basis of Normal Hematopoiesis and Hematological Disorders: Therapeutical Implications

Abstract

We report a SAR study on branched peptide-like ligands, which gives an important insight into structural requirements for VEGF-A₁₆₅/NRP-1 complex inhibitors.

Funder

European Cooperation in Science and Technology

Uniwersytet Warszawski

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/MD/C8MD00537K

Reference61 articles.

1. Neuropilin‐1 expression by tumor cells promotes tumor angiogenesis and progression

2. Neuropilin-1 Is Expressed by Endothelial and Tumor Cells as an Isoform-Specific Receptor for Vascular Endothelial Growth Factor