Catalyst-free, one-pot, four-component green synthesis of functionalized 1-(2-fluorophenyl)-1,4-dihydropyridines under ultrasound irradiation
Author:
Affiliation:
1. School of Chemistry and Physics
2. University of Kwa-Zulu Natal
3. Durban
4. South Africa
Abstract
A catalyst-free synthesis protocol for functionalized 1,4-dihydropyridines under ultrasonic irradiation in aqueous ethanol is reported with excellent yields. Eleven new compounds are synthesized using dimethylacetylenedicarboxylate, 2-fluoroaniline, malononitrile and various substituted aldehydes.
Publisher
Royal Society of Chemistry (RSC)
Subject
Materials Chemistry,General Chemistry,Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2016/NJ/C5NJ03574K
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