Quantitative analysis of drug tablet aging by fast hyper-spectral stimulated Raman scattering microscopy

Author:

Wei Yuxiao12ORCID,Pence Isaac J.1ORCID,Wiatrowski Anna1,Slade Julia B.1,Evans Conor L.1

Affiliation:

1. Wellman Center for Photomedicine, Massachusetts General Hospital, 149 13th Street, Charlestown, Massachusetts 02129, USA

2. Harvard Medical School, Department of Biological and Biomedical Sciences, 260 Longwood Ave, Boston, Massachusetts 02115, USA

Abstract

Pharmaceutical development of drug tablets requires ensuring chemical uniformity and stability. S4RS imaging of drug tablets can quantify chemical degradation and distribution at a faster speed and higher resolution compared to existing technologies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Reference68 articles.

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