Pd/LA-catalyzed decarboxylation enabled exclusive [5 + 2] annulation toward N-aryl azepanes and DFT insights-Reference-Cited by-同舟云学术

Pd/LA-catalyzed decarboxylation enabled exclusive [5 + 2] annulation toward N-aryl azepanes and DFT insights

Published:2021 Issue:9 Volume:8 Page:1902-1909
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Liu Teng¹²³⁴,Fang Yuqi⁵⁶⁷⁴,Zuo Linhong¹²³⁴,Yang Yulian¹²³⁴,Liu Yin¹²³⁴,Chen Weipeng¹²³⁴,Dang Li⁵⁶⁷⁴^ORCID,Guo Wusheng¹²³⁴^ORCID

Affiliation:

1. Frontier Institute of Science and Technology (FIST)

2. Xi'an Jiaotong University

3. Xi'an 710045

4. China

5. Department of Chemistry and Key Laboratory for Preparation and Application of Ordered Structural Materials of Guangdong Province

6. Shantou University

7. Guangdong 515063

Abstract

A practical approach towards the synthesis of non-fused N-aryl azepane derivatives with diversity is described. DFT calculations revealed the origins of this unusual exclusive [5 + 2] rather than empirical [3 + 2] annulation process.

Funder

Xi’an Jiaotong University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/QO/D1QO00070E

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