Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery-Reference-Cited by-同舟云学术

Affinity of plant viral nanoparticle potato virus X (PVX) towards malignant B cells enables cancer drug delivery

Published:2020 Issue:14 Volume:8 Page:3935-3943
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Shukla Sourabh¹²³⁴^ORCID,Roe Anne Jessica⁵⁶⁷⁴^ORCID,Liu Ruifu⁵⁶⁷⁴,Veliz Frank A.⁸⁶⁷⁴^ORCID,Commandeur Ulrich⁹¹⁰¹¹¹²,Wald David N.⁵⁶⁷⁴,Steinmetz Nicole F.¹²³⁴¹³^ORCID

Affiliation:

1. Department of NanoEngineering

2. University of California San Diego

3. La Jolla

4. USA

5. Department of Pathology

6. Case Western Reserve University

7. Cleveland

8. Department of Biomedical Engineering

9. Department of Molecular Biotechnology

10. RWTH-Aachen University

11. Aachen 52064

12. Germany

13. Department of Bioengineering

Abstract

Plant vital nanoparticle PVX shows a binding affinity towards malignant B cells and traffics to metastatic lymphoma sites in mice challenged with B cell lymphoma, thus enabling NHL-specific drug delivery.

Funder

American Cancer Society

Case Comprehensive Cancer Center, Case Western Reserve University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM00683A

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