Spectrophotometric and spectrofluorimetric determination of mesna, acetylcysteine and timonacic acid through the reaction with acetoxymercuri fluorescein

Author:

Haggag Rim S.12345,Gawad Dina A.12345,Belal Saeid F.12345,Elbardisy Hadil M.12675

Affiliation:

1. Department of Pharmaceutical Analytical Chemistry

2. Faculty of Pharmacy

3. University of Alexandria

4. Alexandria

5. Egypt

6. University of Damanhour

7. Damanhour

Abstract

Simple, sensitive and specific spectrophotometric (Method I) and spectrofluorimetric (Method II) methods were developed for the determination of three sulfur-containing drugs: mesna (MSN), acetylcysteine (ACT) and timonacic acid (TMN).

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference53 articles.

1. The British Pharmacopoeia, Her Majesty's Stationery Office, London, UK, 2013, electronic version

2. S. C. Sweetman , Martindale-The Complete Drug Reference, The Pharmaceutical Press, London, UK, 36th edn, 2009, 964–965, 1028–1029, 1449–1450, 1548–1550, 1708, 2402

3. The United States Pharmacopoeia, Thirty-fourth edn, The National Formulary, twenty ninth edn, The Official Compendia of Standards, Asian edn, United States Pharmacopoeial Convention, Inc., Washington, D.C., 2011, 780, 1759–1760, 3433–3434

4. Kinetic fluorimetric determination of Mesna (Sodium-2-mercaptoethane sulfonate) in drug products through oxidation with cerium(IV)

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