Total synthesis of antiallergic bicyclic peptide seongsanamide A-Reference-Cited by-同舟云学术

Total synthesis of antiallergic bicyclic peptide seongsanamide A

Published:2020 Issue:13 Volume:7 Page:1658-1662
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Han Feipeng¹²³,Guo Yian¹²³^ORCID,Ye Tao¹²³⁴⁵^ORCID

Affiliation:

1. State Key Laboratory of Chemical Oncogenomics

2. Peking University Shenzhen Graduate School

3. China

4. Tsinghua Shenzhen International Graduate School

5. Shenzhen

Abstract

The first total synthesis of antiallergic depsipeptide seongsanamide A has been achieved and also the relative and absolute stereochemistry of the natural product has been confirmed.

Funder

National Natural Science Foundation of China

Shenzhen Peacock Plan

Science, Technology and Innovation Commission of Shenzhen Municipality

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/QO/D0QO00531B

Reference48 articles.

1. Bicyclic Peptides as Next-Generation Therapeutics

2. Bridged bicyclic peptides: Structure and function

3. Bicyclic peptides: types, synthesis and applications

4. Total synthesis reveals atypical atropisomerism in a small-molecule natural product, tryptorubin A

5. Seongsanamides A–D: Antiallergic Bicyclic Peptides from Bacillus safensis KCTC 12796BP

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