Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions-Reference-Cited by-同舟云学术

Laboratory of the future: a modular flow platform with multiple integrated PAT tools for multistep reactions

Published:2019 Issue:9 Volume:4 Page:1571-1578
ISSN:2058-9883
Container-title:Reaction Chemistry & Engineering
language:en
Short-container-title:React. Chem. Eng.

Author:

Sagmeister Peter¹²³⁴⁵,Williams Jason D.¹²³⁴⁵^ORCID,Hone Christopher A.¹²³⁴⁵^ORCID,Kappe C. Oliver¹²³⁴⁵^ORCID

Affiliation:

1. Center for Continuous Synthesis and Processing (CCFLOW)

2. Research Center Pharmaceutical Engineering (RCPE)

3. 8010 Graz

4. Austria

5. Institute of Chemistry

Abstract

The coupling of a modular microreactor platform, real-time inline analysis by IR and NMR, and online UPLC, leads to efficient optimization of a multistep organolithium transformation to a given product without the need for human intervention.

Funder

Österreichische Forschungsförderungsgesellschaft

Publisher

Royal Society of Chemistry (RSC)

Subject

Fluid Flow and Transfer Processes,Process Chemistry and Technology,Chemical Engineering (miscellaneous),Chemistry (miscellaneous),Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/RE/C9RE00087A

Reference82 articles.

1. Pharmaceutical Process Chemistry: Evolution of a Contemporary Data-Rich Laboratory Environment

2. Pharma Industry 4.0: Literature review and research opportunities in sustainable pharmaceutical supply chains

3. Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production

4. Industry Perspectives on Process Analytical Technology: Tools and Applications in API Development

5. Industry Perspectives on Process Analytical Technology: Tools and Applications in API Manufacturing

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