Polymer-loaded hydrogels serve as depots for lactate and mimic “cold” tumor microenvironments-Reference-Cited by-同舟云学术

Polymer-loaded hydrogels serve as depots for lactate and mimic “cold” tumor microenvironments

Published:2020 Issue:21 Volume:8 Page:6056-6068
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Allen Riley¹²³⁴,Ivtchenko Emilie¹²³⁴,Thuamsang Bhasirie¹²³⁴,Sangsuwan Rapeepat¹²³⁴,Lewis Jamal S.¹²³⁴^ORCID

Affiliation:

1. Department of Biomedical Engineering

2. University of California (Davis)

3. Davis

4. USA

Abstract

Peptide hydrogels loaded with granulocyte-macrophage colony stimulating factor and poly-(lactic-co-glycolic acid) microparticles can recapitulate lactate concentrations and the immunosuppressive nature of the tumor microenvironment.

Funder

National Institute of Allergy and Infectious Diseases

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2020/BM/D0BM01196G

Reference58 articles.

1. Immunotherapy as an adjunct to surgery in the treatment of cancer

2. Immune checkpoint inhibitors of PD-L1 as cancer therapeutics

3. Cold Tumors: A Therapeutic Challenge for Immunotherapy

4. Therapeutic Cancer Vaccines

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