A nanoprobe for fluorescent monitoring of microRNA and targeted delivery of drugs-Reference-Cited by-同舟云学术

A nanoprobe for fluorescent monitoring of microRNA and targeted delivery of drugs

Published:2021 Issue:15 Volume:11 Page:8871-8878
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Zuo Chen¹²³⁴⁵,Guo Yongcan³⁶⁷⁸^ORCID,Li Junjie¹²³⁴⁵,Peng Zhiping⁹¹⁰⁴¹¹⁸,Bai Shulian¹²³⁴⁵,Yang Shuangshuang¹²³⁴⁵,Wang Ding¹²³⁴⁵,Chen Hui³¹²¹¹⁸,Xie Guoming¹²³⁴⁵^ORCID

Affiliation:

1. Key Laboratory of Laboratory Medical Diagnostics

2. Ministry of Education

3. Department of Laboratory Medicine

4. Chongqing Medical University

5. Chongqing 400016

6. Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University

7. Luzhou

8. P. R. China

9. Department of Radiological Medicine and Oncology

10. College of Basic Medicine

11. Chongqing

12. The First Affiliated Hospital of Chongqing Medical University

Abstract

A DNA-hybrid-gated core–shell upconversion nanoprobe is prepared for both fluorescent monitoring of miR-21 and on-demand delivery of DOX. It showed good selectivity towards miR-21 and demonstrated specific cytotoxic efficacy towards MCF-7 cells.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA00154J

Reference31 articles.

1. Non-coding RNAs in human disease

2. A microRNA polycistron as a potential human oncogene

3. MicroRNA expression profiles classify human cancers