Modulating the aggregation of human prion protein PrP<sub>106–126</sub> by an indole-based cyclometallated palladium complex-Reference-Cited by-同舟云学术

Modulating the aggregation of human prion protein PrP_106–126 by an indole-based cyclometallated palladium complex

Published:2024 Issue:28 Volume:53 Page:11995-12006
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Chauhan Rahul¹,Navale Govinda R.¹^ORCID,Saini Saakshi²,Panwar Abhishek³,Kukreti Prashant¹,Saini Rajat¹,Roy Partha²,Ghosh Kaushik¹²^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology, Roorkee 247667, Uttarakhand, India

2. Department of Biosciences and Bioengineering, Indian Institute of Technology, Roorkee 247667, Uttarakhand, India

3. Department of Chemistry, National Institute of Technology Manipur, Langol 795004, India

Abstract

The aggregation of PrP106–126 peptide is responsible for various prion diseases. In this study, a palladium complex is synthesized and utilized for inhibition study of peptide aggregation through various spectroscopic and microscopic techniques.

Funder

Council of Scientific and Industrial Research, India

Department of Science and Technology, Ministry of Science and Technology

Ministry of Human Resource Development

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/DT/D4DT00704B

Reference80 articles.

1. Hallmarks of neurodegenerative diseases

2. Second Sphere Interactions in Amyloidogenic Diseases

3. Amyloid-type Protein Aggregation and Prion-like Properties of Amyloids

4. Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

5. Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases

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