Back to the oligomeric state: pH-induced dissolution of concanavalin A amyloid-like fibrils into non-native oligomers
Author:
Affiliation:
1. Department of Physics and Chemistry
2. University of Palermo
3. Palermo
4. Italy
5. Section for Biologics
6. Department of Pharmacy
7. Faculty of Health and Medical Sciences
8. University of Copenhagen
9. Copenhagen
10. Aten Center
Abstract
Changes in solution pH may result in modifications of energy landscape shape making readily accessible or more favourable native or oligomeric intermediate minima with respect to the fibrillar one.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA16690C
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