Visible-light-mediated photocatalytic sequential N-arylation: an eco-friendly synthetic route to unsymmetrical diarylamines and the imatinib drug

Author:

Sana Sravani1,Dastari Sowmya1,Reddy Dannarm Srinivas2,Tokala Ramya1,Sathish Manda3ORCID,Sonti Rajesh2,Shankaraiah Nagula1ORCID

Affiliation:

1. Department of Medicinal Chemistry, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad - 500 037, India

2. Department of Pharmaceutical Analysis, National Institute of Pharmaceutical Education and Research (NIPER), Hyderabad - 500 037, India

3. Centro de Investigación de Estudios Avanzados del Maule (CIEAM), Vicerrectoría de Investigación y Postgrado, Universidad Católica del Maule, Talca-3460000, Chile

Abstract

A sustainable photoredox-mediated protocol for the construction of unsymmetrical diarylamines using a Cu/Ru catalytic system has been successfully devised with a wide substrate scope and good yields.

Funder

Department of Pharmaceuticals, Ministry of Chemicals and Fertilizers, India

Fondo Nacional de Desarrollo Científico y Tecnológico

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

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