Betulinic acid acetate, an antiproliferative natural product, suppresses client proteins of heat shock protein pathways through a CDC37-binding mechanism
Author:
Affiliation:
1. Jiangsu Key Laboratory of Drug Design and Optimization
2. China Pharmaceutical University
3. Nanjing
4. China
5. State Key Laboratory of Natural Medicines
Abstract
CDC37 has emerged as a promising target in antitumor chemotherapy because of its significant role in oncogenic signaling networks.
Funder
National Natural Science Foundation of Jiangsu Province
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA04776A
Reference23 articles.
1. Association of heat-shock proteins in various neurodegenerative disorders: is it a master key to open the therapeutic door?
2. HSP90 and the chaperoning of cancer
3. Targeting the dynamic HSP90 complex in cancer
4. Heat Shock Protein 90: Inhibitors in Clinical Trials
5. Inhibition of HSP90 molecular chaperones: moving into the clinic
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