Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents-Reference-Cited by-同舟云学术

Design, synthesis and evaluation of new tricyclic endoperoxides as potential antiplasmodial agents

Published:2014 Issue:28 Volume:12 Page:5212-5221
ISSN:1477-0520
Container-title:Org. Biomol. Chem.
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Ruiz Jérémy¹²³⁴,Mallet-Ladeira Sonia⁵⁶³⁷,Maynadier Marjorie⁸⁹¹⁰¹¹,Vial Henri⁸⁹¹⁰¹¹,André-Barrès Christiane¹²³⁴

Affiliation:

1. Laboratoire de Synthèse et de Physicochimie de Molécules d'Intérêt Biologique

2. UMR CNRS 5068

3. Université Paul-Sabatier

4. F-31062 Toulouse cedex 4, France

5. Institut de Chimie de Toulouse

6. FR2599

7. F-31062 Toulouse cedex 9, France

8. Dynamique des Interactions Membranaires Normales et Pathologiques

9. UMR CNRS 5235

10. Université Montpellier 2

11. F-34095 Montpellier cedex 5, France

Abstract

New tricyclic endoperoxides were obtained by a diastereoselective autoxidation; combined with 7-chloro-4-aminoquinoline, they display good antiplasmodial activities.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/OB/C4OB00787E

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