Gd<sup>III</sup> and Ga<sup>III</sup> complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution-Reference-Cited by-同舟云学术

Gd^III and Ga^III complexes with a new tris-3,4-HOPO ligand as new imaging probes: complex stability, magnetic properties and biodistribution

Published:2022 Issue:16 Volume:51 Page:6436-6447
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Chaves Silvia¹^ORCID,Gwizdała Karolina¹²^ORCID,Chand Karam¹^ORCID,Gano Lurdes³^ORCID,Pallier Agnès⁴,Tóth Éva⁴^ORCID,Santos M. Amélia¹^ORCID

Affiliation:

1. Centro de Química Estrutural, Institute of Molecular Sciences, Departamento de Engenharia Química, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais 1, 1049-001, Lisboa, Portugal

2. Faculty of Chemistry, Gdansk University of Technology, Gabriela Narutowicza 11/12, 80-233 Gdansk, Poland

3. Centro de Ciências e Tecnologias Nucleares (C2TN), Instituto Superior Técnico, Universidade de Lisboa, Estrada Nacional 10, 2695-066 Bobadela LRS, Portugal

4. Centre de Biophysique Moléculaire, CNRS UPR 4301, Université d'Orléans, rue Charles Sadron, 45071 Orléans, France

Abstract

MIII complexes (M = Ga, Gd) with a new tris-3,4-HOPO ligand (L2) with biotargeting capacity, have been studied for their thermodynamic stability, magnetic properties and in vivo biodistribution, envisaging potential applications in diagnostic imaging.

Funder

Fundação para a Ciência e a Tecnologia

European Cooperation in Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/DT/D2DT00066K

Reference32 articles.

1. Multimodality Imaging Probes: Design and Challenges

2. Next-Generation Magnetic Resonance Imaging Contrast Agents

3. Chemistry of MRI Contrast Agents: Current Challenges and New Frontiers

4. Gallium-68 Complexes Conjugated to Pittsburgh Compound B: Radiolabeling and Biological Evaluation

5. A 68Ga complex based on benzofuran scaffold for the detection of β-amyloid plaques

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